This is my presentation from Icon UK in September which discusses making client decisions whilst keeping Domino, the best mail server in the world, as your underlying architecture
How often do you hear that the business is discussing moving mail platforms because “our users want X” where X is nothing to do with the server and everything to do with the client UI. Domino remains the best mail server available but often user dissatisfaction drives a move and that comes from being asked to use the wrong client or from a bad deployment. If you’re using Domino you have an ever expanding range of clients to choose from browsers, iNotes, Verse, Traveler with iOS integration, Android applications, POP3 and IMAP.
The full presentation is here
I am wondering if you have any experience with using POP3 client with Domino. Our internal testing a few months ago show a very poor performance (POP3 task on server became non-responsive and server have to be restarted) and based on that we recommend using IMAP instead of POP3.